Validation of an ELISA for the diagnosis of human trichinellosis
نویسندگان
چکیده
Validation of an ELISA for the diagnosis of human trichinellosis 1 2 Running title: Serodiagnosis of human trichinellosis 3 4 Maria Angeles Gómez-Morales, 1* Alessandra Ludovisi, 1 Marco Amati, 1 Simona Cherchi, 1 5 Patrizio Pezzotti, 2 and Edoardo Pozio 1 6 7 Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di 8 Sanità, 1 and Agenzia di Sanità Pubblica, 2 Rome, Italy 9 10 Corresponding author: 11 Maria Angeles Gómez-Morales 12 Department of Infectious, Parasitic and Immunomediated Diseases, 13 Istituto Superiore di Sanità 14 viale Regina Elena. 299 15 00161 Rome, Italy 16 Tel. +39 06 4990 3379 17 Fax +39 06 4990 3561 18 Email: [email protected] 19 AC CE PT ED Copyright © 2008, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. Clin. Vaccine Immunol. doi:10.1128/CVI.00257-08 CVI Accepts, published online ahead of print on 30 September 2008
منابع مشابه
Validation of an enzyme-linked immunosorbent assay for diagnosis of human trichinellosis.
Trichinellosis is a zoonotic disease caused by the consumption of raw or semiraw meat from different animals harboring Trichinella larvae in their muscles. Since there are no pathognomonic signs, diagnosis can be difficult; for this reason, serology is important. The objective of this study was to validate an enzyme-linked immunosorbent assay (ELISA) using excretory/secretory antigens to detect...
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INTRODUCTION The most important confirmative diagnostic test for trichinellosis is the presence of the muscle larvae in a tissue biopsy but this direct method has a low sensitivity of light and moderate infections. The aim of presented study was to compare the usefulness of the results obtained by three ELISA procedures for Trichinella spp. diagnosis in human outbreaks. MATERIALS AND METHODS ...
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